Zeiss fundus camera

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Source: Daily Dose of Eye Care

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FDA Authorizes Clinical Trial for CRISPR/Cas9 Therapy for LCA 10

Editas Medicine , a company developing gene-editing treatments, has received authorization from the US Food and Drug Administration to launch a clinical trial for its emerging CRISPR/Cas9 therapy for people with a mutation in the gene CEP290, which causes Leber congenital amaurosis 10 (LCA10). LCA causes severe vision loss or blindness at birth. Known as EDIT-101, the treatment will be evaluated in a Phase 1/2, dose-escalation clinical trial.  The company expects to enroll 10 to 20 patients. Further details and contact information for the study will be listed soon at www.clinicaltrials.gov . EDIT-101 targets a specific mutation, “c.2991+1655A>G” in intron 26, of the CEP290 gene. Editas has earned a $25 million milestone payment from Allergan as part of a drug-development alliance. “We are very pleased with this historic milestone in the treatment of inherited retinal diseases,” says Stephen Rose, PhD, chief scientific officer, Foundation Fighting Blindness. “EDIT-101 is the fi...
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The Effects of Screen Time for Kids

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As the holidays approach, there are many digital gadgets children may be asking for or receiving. Some of the more popular gifts include flat-screen TVs, tablets, phones, streaming devices (Firestick, Roku, Apple TV, etc.), and gaming systems. Even Fisher-Price is offering the Think & Learn Smart Cycle, which syncs with a tablet for kids to play learning games while they ride the attached stationary bike. While some of these devices add learning opportunities, most of them come with added screen time, which may be cause for concern. The effects of excessive screen time are usually considered when adults work on computers for 8+ hours a day , but parents are starting to notice their children’s symptoms. Device Use & Symptoms in Young People In a survey of 300 US parents, half of the participants reported that their children spend too much time on devices. However, over two-thirds believe device usage won’t change and say they won’t be cutting back any time soon. Because of thi...
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AGTC Announces Topline Interim Six-Month Data of XLRS Gene Therapy from Ongoing Phase 1/2 Clinical Trial

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